2-(1H-1,2,4-triazol-1-yl)propanoic acid hydrochloride
2-[1,2,4]Triazol-1-yl-propionic acidhydrochloride
CAS: 1185297-13-5
Molecular Formula: C5H8ClN3O2
2-(1H-1,2,4-triazol-1-yl)propanoic acid hydrochloride - Names and Identifiers
2-(1H-1,2,4-triazol-1-yl)propanoic acid hydrochloride - Physico-chemical Properties
| Molecular Formula | C5H8ClN3O2 |
| Molar Mass | 177.59 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD06801318 |
2-(1H-1,2,4-triazol-1-yl)propanoic acid hydrochloride - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
2-(1H-1,2,4-triazol-1-yl)propanoic acid hydrochloride - Introduction
2-[1,2,4] triazolylpropionic acid hydrochloride (2-[1,2,4]Triazol-1-yl-propionic acidhydrochloride), also known as TAPAH, has the following properties:
Appearance: TAPAH exists as a white solid.
Solubility: TAPAH has high solubility in water.
2-[1,2,4] triazolyl propionic acid hydrochloride is mainly used in the following aspects:
1. As a catalyst in organic synthesis: TAPAH can be used as a catalyst for the synthesis of compounds, especially in the reaction that requires the introduction of triazole functional groups during the synthesis process.
2. As a pharmaceutical intermediate: TAPAH can be used as an intermediate for the preparation of various drugs, such as anti-tumor drugs, anti-tuberculosis drugs, etc.
3. As an antifungal agent: TAPAH has antifungal activity and can be used to prepare new antifungal drugs.
2-[1,2,4] triazolylpropionic acid hydrochloride is generally prepared by chemical synthesis. The specific steps can be adjusted according to experimental requirements, but usually include the following basic steps: 2-[1,2,4] triazolyl ethyl formamide is first synthesized, and then it is acidified to obtain 2-[1,2,4] triazolyl propionic acid. Finally, the acid is reacted with hydrochloric acid to give 2-[1,2,4] triazolylpropionic acid hydrochloride.
No clear published data on the specific toxicity and hazardous properties of 2-[1,2,4] triazolylpropionic acid hydrochloride have been reported regarding safety information. During use, care should be taken to prevent contact with skin and eyes and maintain good ventilation conditions. When using and storing, the relevant safety operation procedures should be observed, and the corresponding personal protective measures should be taken according to the specific situation. During use, it is recommended to wear appropriate personal protective equipment, such as laboratory gloves, protective glasses, etc.
Appearance: TAPAH exists as a white solid.
Solubility: TAPAH has high solubility in water.
2-[1,2,4] triazolyl propionic acid hydrochloride is mainly used in the following aspects:
1. As a catalyst in organic synthesis: TAPAH can be used as a catalyst for the synthesis of compounds, especially in the reaction that requires the introduction of triazole functional groups during the synthesis process.
2. As a pharmaceutical intermediate: TAPAH can be used as an intermediate for the preparation of various drugs, such as anti-tumor drugs, anti-tuberculosis drugs, etc.
3. As an antifungal agent: TAPAH has antifungal activity and can be used to prepare new antifungal drugs.
2-[1,2,4] triazolylpropionic acid hydrochloride is generally prepared by chemical synthesis. The specific steps can be adjusted according to experimental requirements, but usually include the following basic steps: 2-[1,2,4] triazolyl ethyl formamide is first synthesized, and then it is acidified to obtain 2-[1,2,4] triazolyl propionic acid. Finally, the acid is reacted with hydrochloric acid to give 2-[1,2,4] triazolylpropionic acid hydrochloride.
No clear published data on the specific toxicity and hazardous properties of 2-[1,2,4] triazolylpropionic acid hydrochloride have been reported regarding safety information. During use, care should be taken to prevent contact with skin and eyes and maintain good ventilation conditions. When using and storing, the relevant safety operation procedures should be observed, and the corresponding personal protective measures should be taken according to the specific situation. During use, it is recommended to wear appropriate personal protective equipment, such as laboratory gloves, protective glasses, etc.
Last Update：2024-04-10 22:41:30
